My Autophagy Blog

It's all about Lysosomes. If you want to know how your body stays young or kills disease or removes junk from your body, then look at Lysosomes. They'll tell you everything you need to know about the fountain of youth. Ninja Nerd has the best explanation: https://www.youtube.com/watch?v=QtGMAgxv72Y&t=1s Pierre

 The question remains. Have I stopped aging.?  The strangest thing happened. I started understanding autophagy and lysosome behavior. I get it, it actually works. This is not some kind of bs i've been told about or something I've read about someone who guesses how something might works. No, nothing like that.This is real. We figured out how thw human cell works and more than that, we know we can affect it by doing certain things, like fasting, for instance.  I'm fasting, pretty regularly, and I fast at a high level for 4 days, just water and coffee and tea, I know, it's very difficult. And most people want to do fasting mimicking, because you get to eat at a low level, and it works.  Fasting, mimicking diet actually works and Dr. Longo has proven that it actually does. He shows that if you fast with his mimicking diet. Then, if you do it for 3 months, five days once a month, you will drop two and a half years of biologic age.  Sure. Soon enough, there will ...

 So I've looked at doctor Longo's studies on fasting. His fasting is different. He uses fastin mimicking diets and he shows a reduction of age from fasting.  After about 3 months of fasting with his protocol, he shows 2.5 years of chronological biologic age reduction. They do one 5 day mimicking fast a month. This is pretty significant. The mimicking diet he uses doesn't go as deep as the water fast I do even though it does still show a reduction of biologic age, which is really interesting. So going by this protocol and comparing it to water fasting, water fasting reduces age even more rapidly. What I'm doing, with water fasting, lowers the GK I below 1.5.   I do that because of the cysts  that used to grow underneath my retina. Now I'm showing signs of reducing my age even more. Interesting. If he has a book, Im going to read it. Pierre

 There is a machine in the brain that moves us towards food. Its not hunger. Hunger is pretty obvious, this machine of the brain is more subtle and more powerful. It diminishes the will to continue fasting by lowering your ability to be self determined.   I watch for it now. Part of this machine starts by wanting to crunch or chew something. It uses your imagination by imagining food moving down your throat and filling your stomach. My method for conquering this powerful mechanism is to leave my home. This keeps me away from the food in the kitchen. Here though, is my opportunity to conquer this machine. It has taken years of distance from my kitchen to get used to the idea that I must eat. Breaking the habit of always snacking and eating meals is not a habit you can change easily. I was destined for blindness. So I had an incentive to conquer this powerful habit. Wet macular degeneration is a weird disease. It takes away pieces of your sight in the center of your vision ...

 I quit my 4 day fast short of 2 days.  The thing is, my urine had an odor. My question was why? So here goes. A little after 24 hours, your digestion starts to run out of glucose. So the body then starts supplementing glucose from it's store of glucose from your organs.  The store molecule is called Glycogen. Glycogen is glucose stored with 3 parts water, 1 part glucose. So, after 24 hours, when the Glycogen starts inserting glucose into your bloodstream, that 3 parts of water starts going out as urine. So you pee every 20 or 30 minutes until the store is empty. Staying close to a bathroom is imperative.  Ok, after the fast ended, my pee was really strong. I asked Gemini why my pee might smell so bad. And it said that I was probably short of water, that is dehydrated. There are other reasons, of course, but that was probably the main reason.  After a bit of analysis, I thought, is it possible that my glycogen store was soaking up the water that I was putting in...

 When Dolly was cloned, she didnt have any of the diseases that weren't genetic. The ones that accumulate from age. It appears that Autophagy can reduce age as this study implies: https://www.google.com/amp/s/etedge-insights.com/featured-insights/ari-pune-study-recasts-ageing-as-niche-cell-breakdown/amp/ This research shows that stem cells stay pristine while its the normal cells that degenerate.   That's a big one because thats what autophagy attacks. Broken organelles and broken cells.  We're entering a new age, one where we will live extremely long lives. Look at the fact of how we pass on our genes. Yes there are mutations but they are rare. Now imagine that technique is supported by proper fasting, which amplifies autophagy. I started with saving my eyes from wet macular, an old age disease that shows up, due to a lack of autophagy and wound up chasing the fountain of youth. Can you blame me? Im 74 and when I look in the mirror I see an old man. Im not 100% sure...